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Suarez, A. At coitus, human sperm are deposited into the anterior vagina, where, to avoid vaginal acid and immune responses, they quickly contact cervical mucus and enter the cervix. Cervical mucus filters out sperm with poor morphology and motility and as such only a minority of ejaculated sperm actually enter the cervix.

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The human reproductive system usually involves internal fertilization by sexual intercourse. In this process, the male inserts his penis into the female 's vagina and ejaculates semenwhich contains sperm. A small proportion of the sperm pass through the cervix into the uterus, and then into the Fallopian tubes for fertilization of the ovum.

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Sperm chromatin integrity has been being recognized as an important factor in male fertility. During normal fertilization, high quality sperm with intact chromatin are selected through natural selection in journey from vagina to fallopian tube. Therefore sperm with DNA breakage have the opportunity to fertilize the egg which may lead to decreased embryo quality and implantation rate.

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Fertilization occurs when a sperm and an oocyte egg combine and their nuclei fuse. Because each of these reproductive cells is a haploid cell containing half of the genetic material needed to form a human being, their combination forms a diploid cell. This new single cell, called a zygotecontains all of the genetic material needed to form a human—half from the mother and half from the father.

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Reproduction is the process by which organisms make more organisms like themselves. But even though the reproductive system is essential to keeping a species alive, unlike other body systems, it's not essential to keeping an individual alive. In the human reproductive process, two kinds of sex cells, or gametes GAH-meetzare involved.

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