Bryan Larsen, Gilles R. The microbiological flora of the lower female genital tract provides a dynamic, complex example of microbial colonization, the regulation of which is not fully understood. When an exogenous bacterial species, with its array of virulence factors, is introduced into the host, disease does not always occur.
Lactobacillus is a genus of Gram-positivefacultative anaerobic or microaerophilicrod-shaped, non- spore -forming bacteria. In humans, they constitute a significant component of the microbiota at a number of body sites, such as the digestive systemurinary system [ citation needed ]and genital system. In women of European ancestry, Lactobacillus species are normally a major part of the vaginal microbiota.
Metrics details. The vaginal microbiome plays an important role in urogenital health. We set up qPCR assays for a selection of seven species and defined the temporal variation over three menstrual cycles in a healthy Caucasian population with a normal Nugent score. Temporal stability of the Lactobacillus species counts was high with L.
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Biotechnology and Bioprocess Engineering. Bacterial vaginosis can be treated by restoring the normal vaginal flora using lactobacilli. Lactobacillus crispatus KLB46 that was isolated from the human vagina has a strong antimicrobial activity and was grown in a batch and in a continuous fermentor.
Please make sure that you are posting in the form of a question. Please enter a question. Vaginal microflora forms a mutually beneficial relationship with your body and plays a protective role in preventing colonization of the host by pathogenic organisms that cause vaginosis, yeast infections, sexually transmitted infections STIand other urinary tract infections.
Use the link below to share a full-text version of this article with your friends and colleagues. Learn more. There seems to be an association between the absence of, or low concentrations of, vaginal lactobacilli and the development of BV.
The human body is colonized by a vast number of microorganisms collectively referred to as the human microbiota. One of the main microbiota body sites is the female genital tract, commonly dominated by Lactobacillus spp. The most frequently isolated species are Lactobacillus crispatusLactobacillus gasseriLactobacillus jensenii and Lactobacillus iners. Residing at the port of entry of bacterial and viral pathogens, the vaginal Lactobacillus species can create a barrier against pathogen invasion since mainly products of their metabolism secreted in the cervicovaginal fluid can play an important role in the inhibition of bacterial and viral infections.