Vagifem vaginal tablets or pessaries contain the active ingredient estradiol hemihydrate, which is a naturally occuring form of the main female sex hormone, oestrogen. Womens'' ovaries gradually produce less and less oestrogen in the period up to the menopause, and oestrogen blood levels decline as a result. The declining levels of oestrogen can cause distressing symptoms, and often affect the delicate lining of the vagina.
Reuters Health - For women bothered by vaginal symptoms after menopause, prescription local estrogen treatments and expensive specialty lubricants may provide relief, but no more so than a dummy drug, researchers say. Mitchell and colleagues enrolled postmenopausal women between ages 55 and 64 with moderate to severe symptoms of vulvovaginal itching, dryness, irritation and pain during intercourse in a week randomized clinical trial that took place in at Kaiser Permanente Washington Health Research Institute in Seattle and the University of Minnesota in Minneapolis. At the outset of the study, all the participants rated the severity of their most bothersome symptom at about 2.
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Vaginal estrogen is a form of estrogen that is delivered by intravaginal administration. Vaginally administered estrogens are thereby exerting their effects mainly in the nearby tissue, with more limited systemic effects compared to orally administered estrogens. Vaginally administered estrogen are usually used to treat some menopausal symptoms that are isolated to the vaginavulva and urethra.
Vaginal dryness probably results from changes that occur when estrogen levels drop. Low estrogen causes the vagina and surrounding connective tissue to lose elasticity and the tissue that lines the vagina becomes thinner and more fragile. How does vaginal dryness feel?
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The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. For Atrophic Vaginitis "Hi I have Atrophic Vaginitis using vagifem for a few months, all was well but recently my breasts are like cannonballs and tender has anyone experienced this?
Vulvovaginal atrophy [VVA] is defined as inflammation of the vaginal epithelium due to atrophy secondary to decreased levels of circulating estrogen. There is currently only one approved method for the treatment of VVA, and that is the administration of exogenous estrogens. Overall, the ideal VVA treatment must have benefits, minimize risks, and enhance compliance in the patient while optimizing cost-effectiveness. Women have been very reluctant to take hormone therapy due to widely publicized results of the risks associated with hormone therapy.